| CODE | DESCRIPTION | PRIORITY | LICENSE |
|---|---|---|---|
| 98002 IFNa5 | Interferon alfa 5 use as antiviral for hepatitis C treatment | Sol. ES9801003; 13/05/1998 | DIGNA BIOTECH |
| 98003 iTGFb1 | Peptide inhibitors of TGF beta 1 | Sol. ES9802465; 24/11/1998 | DIGNA BIOTECH |
| 01005 snRNPU1mod | Reversible inhibition of gene expression by modified ribonucleoprotein U1 | Sol. ES200100765; 30/03/2001 | Joint owner with University of Rutgers (USA) |
| 01008 CT-1 | Use of Cardiotrophine (CT-1) for the treatment of human liver diseases | Sol. ES200102120; 21/09/2001 | DIGNA BIOTECH |
| 02007 iTGFb1 II | Peptides Inhibitors of TGF-beta 1 (II) | Sol. ES200302020; 22/08/2003 | DIGNA BIOTECH |
| 03001 EPCR | New method for thrombosis risk evaluation by measuring EPCR auto-antibody in plasma | Sol. ES200400269; 06/02/2004 | DIGNA BIOTECH |
| 03004 AdSFV Vec | Hybrid virus (Adenovirus-alfa/ Semliky Forest) to administer and express therapeutics genes in tumour cells | Sol. ES200401219; 20/05/2004 | DIGNA BIOTECH |
| 04005 AR | Use of anfirreguline as acute liver protectant agent | Sol. ES200401776; 20/07/2004 | DIGNA BIOTECH |
| 04011 ApoA1 HCC | Oxidised Apo A1 as early markers of Hepatocellular carcinoma | Sol. ES200402989; 16/12/2004 | DIGNA BIOTECH |
| 05003 MAPC | Vascular/Lymphatic Endothelial Cells derived from mature adult stem cell | Sol.US 60/652,015; 10/02/200 | Joint owner with University of Minnesota (USA) |
| 04007 nsEPCR | New soluble ePCR protein as trombotic marker and potential therapeutic agent | Sol. ES200500623; 17/03/2005 | DIGNA BIOTECH |
| 04016 MTA Autoin | 5'-metiltioadenosina (MTA) in the prevention and treatment of autoimmune diseases | PCT/ES 2005/000139; 17/03/2005 | DIGNA BIOTECH |
| 05004 EWS-FLI1 | Animal model of human Ewing sarcoma | PCT/ES 2005/000234; 29/04/2005 | |
| 05008 IFNa.CT1 | Use of cardiotropline-1 (CT-1) and alfa interferon (IFNa) for combined treatment in viral diseases | Sol. ES200501468; 16/06/2005 | DIGNA BIOTECH |
| 05012 URIFIB | Fibrosis markers in urine | Sol. ES200501611; 01/07/2005 | DIGNA BIOTECH |
| 04018 EDA Vac | Use of EDA as immune-modulator agent | Sol. ES200501412; 13/06/2005 | DIGNA BIOTECH |
| 05013 HCC.Prof | A selection of hepatocellular carcinoma markers | Sol. ES200502369; 29/09/2005 | DIGNA BIOTECH |
| 05009 HCV poliIC.aCD40 | Immune-stimulatory combination for hepatitis C prevention | Sol. ES200502446; 07/10/2005 Sol. ES20060156; 09/06/2006 |
DIGNA BIOTECH |
| 05030 iTGFb1 INMUN | Use of peptides inhibitor of TGF-beta1 as a immune response modulator | PCT/ES 2005/002446; 24/10/2005 | DIGNA BIOTECH |
| 05019 CRAds | New recombinant adenovirus with conditionated replication | Sol. ES200503047; 12/12/2005 | DIGNA BIOTECH |
| 05029 DTh.panDR | New synthetic peptides as T helper (DTh) determinant for universal DR | Sol. ES200503169; 23/12/2005 | |
| 06010 BrC.Predictor | 11q deletion as a molecular genetic marker in breast cancer | Sol. US11/382,99; 12/05/2006 | Joint owner with University of California (USA) |
| 05018 Línea NSCLC | Experimental model for bond metastasis from lung cancer | Sol. ES200602349; 15/09/200 | |
| 06016 iIL10 | IL-10 inhibitors peptides (iIL-10) | Sol. ES200700806; 27/03/2007 | |
| 06022 Prot.Prod | Viral vector as producer for stable cell line generation | Sol. ES200700882; 03/04/2007 | |
| 06024 iFoxp3 | Escurfine inhibitors peptides(i Fox p3) | Sol. ES200703052; 19/11/2007 | DIGNA BIOTECH |
| 06031 MMP10.coag | Metalloproteinase 10 as adjuvant for trombolitic treatment (MMP10) | Sol. ES200700501; 26/02/2007 | DIGNA BIOTECH |
| 07014 aMMP10.Blood | Metalloproteinase 10 Inhibitors as anti-fibrinolitic treatment (iMMP10) | Sol. ES200701786; 26/06/2007 | DIGNA BIOTECH |
| 07016 TGFb1-MMPs | Metalloproteinase in combination with iTGF beta for metastasis treatment (MMPs+iTGFbeta-1) | Sol. ES200702309; 20/08/2007 | DIGNA BIOTECH |
| 05033 PPARa CPH | Inhibitors of PPAR alfa truncated for heart failure prevention in hypertension (iPPAR truncated) | Sol. ES200702625; 05/10/2007 | DIGNA BIOTECH |
| 07005 IFN.CD137 | Association of alfa interferon to 4-1BB agonist antibodies for antitumoral treatment (alfa INF+4-1BB agonist) | Sol. ES200702961; 07/11/2007 | |
| 07027 IL12.iTGFb1 | iTGF beta 1 as adjuvant for the antitumoral effect of IL12 induced expression (IL12+iTGF beta1) | Sol. ES200800417; 15/02/2008 | |
| 07024 U1.RNAi | Synergy of silencing post-transcriptional genes combining mRNAi and snRNP (mRNAi + sn RNP U1 | Sol. ES200800222; 29/01/2008 | |
| 06027 PCP.PCPE | Methods for the treatment of cardiac disease associated to myocardial fibrosis | PCT/EP 2008/051347; 04/02/2008 |
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